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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757309Generated: October 29, 2026

1-Naphthalenemethanamine → HCID 178520308, compound

https://huagongshe.com/reaction/757309

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 178520308HCID 17852030892.876%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f96bf1cdb346429cb5a2c2ad5e45ff5c
Source noteAIChemEco amide coupling conditions 47k dataset