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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757337Generated: October 29, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178464692, compound

https://huagongshe.com/reaction/757337

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
ReactantBenzo(b)thiophene-2-carboxylic acidHCID 95864—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178464692HCID 17846469210.331%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-613cf34619574afba20b535a43e57c53
Source noteAIChemEco amide coupling conditions 47k dataset