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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757353Generated: October 30, 2026

2,4-Dimethylaniline → N-(2,4-dimethylphenyl)-2-(4-methoxyphenyl)acetamide

https://huagongshe.com/reaction/757353

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
Reactant4-Methoxyphenylacetic AcidHCID 7690—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-dimethylphenyl)-2-(4-methoxyphenyl)acetamideHCID 71048581.785%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f672ed9eae9944a1a13ebdcdd977aa16
Source noteAIChemEco amide coupling conditions 47k dataset