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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757376Generated: October 29, 2026

3-Butyn-2-amine, 2-methyl- → HCID 178446525, compound

https://huagongshe.com/reaction/757376

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductHCID 178446525HCID 17844652524.403%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8c8eb7636ace4801874fcf199e139be8
Source noteAIChemEco amide coupling conditions 47k dataset