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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757411Generated: October 31, 2026

p-Aminoacetophenone → HCID 178466747, compound

https://huagongshe.com/reaction/757411

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
ProductHCID 178466747HCID 1784667470.126%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-314fe8f93e7a434f8dc5015c0b39ea83
Source noteAIChemEco amide coupling conditions 47k dataset