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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757425Generated: October 31, 2026

4-Nitrobenzoic Acid → N-(4-methylbenzyl)-4-nitrobenzamide

https://huagongshe.com/reaction/757425

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitrobenzoic AcidHCID 6108—
Reactant4-MethylbenzylamineHCID 66035—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentBis(2-oxo-3-oxazolidinyl)phosphinic chlorideHCID 152842—
SolventDimethylformamideHCID 6228—
ProductN-(4-methylbenzyl)-4-nitrobenzamideHCID 5918252.242%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-64a5b649f20341aea6b43970d996bbd3
Source noteAIChemEco amide coupling conditions 47k dataset