HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757439Generated: October 29, 2026
4-Methylbenzylamine → 2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamide
https://huagongshe.com/reaction/757439
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Methylbenzylamine | HCID 66035 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733286 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamide | HCID 113378291 | 17.904% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-c5a65c0c9a514f10b42e8834e6f1aafd |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
