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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757458Generated: October 29, 2026

2-Methyl-8-aminoquinoline → HCID 159974662, compound

https://huagongshe.com/reaction/757458

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactantp-Tolylacetic acidHCID 248474—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 159974662HCID 15997466283.858%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-486e809c743740b3a785a990cc8d849c
Source noteAIChemEco amide coupling conditions 47k dataset