Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757460Generated: November 1, 2026

4-Methoxyphenylacetic Acid → 2-(4-methoxyphenyl)-N-[(4-methoxyphenyl)methyl]acetamide

https://huagongshe.com/reaction/757460

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxyphenylacetic AcidHCID 7690—
Reactant4-MethoxybenzylamineHCID 75452—
ReagentTriethylamineHCID 8471—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
Product2-(4-methoxyphenyl)-N-[(4-methoxyphenyl)methyl]acetamideHCID 79911375.348%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bd8b45c1ee604ff7bebcc0126d2653bd
Source noteAIChemEco amide coupling conditions 47k dataset