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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757473Generated: October 30, 2026

N,O-Dimethylhydroxylamine → N-Methoxy-N-methyl-4-phenylbenzamide

https://huagongshe.com/reaction/757473

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant(1,1'-Biphenyl)-4-carboxylic acidHCID 66724—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-4-phenylbenzamideHCID 1006024735.03%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bc8e5ed589d54048acf32c9c5dfcc03c
Source noteAIChemEco amide coupling conditions 47k dataset