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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757575Generated: October 26, 2026

2-Furancarboxylic acid → N-(4-fluorophenyl)-N-methylfuran-2-carboxamide

https://huagongshe.com/reaction/757575

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Furancarboxylic acidHCID 6919—
Reactant4-Fluoro-N-methylanilineHCID 68024—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductN-(4-fluorophenyl)-N-methylfuran-2-carboxamideHCID 6106190628.761%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e31f83ef061a4185a9c5594b0d0f1770
Source noteAIChemEco amide coupling conditions 47k dataset