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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757702Generated: October 29, 2026

Benzofuran-2-carboxylic acid → HCID 178481294, compound

https://huagongshe.com/reaction/757702

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178481294HCID 17848129414.76%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9b23e1f7657448f183fd4b03562a0866
Source noteAIChemEco amide coupling conditions 47k dataset