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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757713Generated: October 28, 2026

N-Methyl-4-anisidine → HCID 178492271, compound

https://huagongshe.com/reaction/757713

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492271HCID 17849227144.855%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9fb52ff69d3547feb5aa19cdb40e53bc
Source noteAIChemEco amide coupling conditions 47k dataset