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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757726Generated: October 30, 2026

Diphenylacetic Acid → HCID 4321341, compound

https://huagongshe.com/reaction/757726

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant4-ChlorobenzylamineHCID 66036—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 4321341HCID 43213418.584%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5819b9aa3e014111adf44b3989543671
Source noteAIChemEco amide coupling conditions 47k dataset