HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Bromide → 3-[4-(3-Phenyl-ureido)-phenyl]-isoxazole-5-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Bromide | HCID 253877 | — |
| Reactant | 3-[4-(3-Phenyl-ureido)-phenyl]-isoxazole-5-carboxylic acid ethyl ester | HCID 67352240 | — |
| Product | 3-[4-(3-Phenyl-ureido)-phenyl]-isoxazole-5-carboxylic acid | HCID 67355011 | 95.6% |
Reaction Steps
The title compound was prepared from 3-[4-(3-phenyl-ureido)-phenyl]-isoxazole-5-carboxylic acid ethyl ester as set forth in example 8 and was obtained in 95.6% yield. Mass (ES+): 324 (M++1); IR (KBr): 3312, 1711, 1645, 1599, 1461; 1H NMR (DMSO-d6) δ: 6.97 (t, 1H), 7.28 (t, 2H), 7.45 (d, 2H), 7.59 (d, 2H), 7.71 (s, 1H), 7.87 (d, 2H), 8.76 (s, 1H), 8.96 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08835428B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-9d69b0bec77c427ebf429443c5479d12 |
| Source note | uspto-grants-2014_09 |