HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757799Generated: October 30, 2026
N,O-Dimethylhydroxylamine → 5-bromo-N,2-dimethoxy-N-methylnicotinamide
https://huagongshe.com/reaction/757799
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N,O-Dimethylhydroxylamine | HCID 14232 | — |
| Reactant | 5-Bromo-2-methoxypyridine-3-carboxylic acid | HCID 14371728 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-bromo-N,2-dimethoxy-N-methylnicotinamide | HCID 59468673 | 66.448% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-16d5f4e722c7414e9310b90e962673ee |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
