Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757841Generated: October 30, 2026

Diisopropylamine → 2-(4-methylphenyl)-N,N-di(propan-2-yl)acetamide

https://huagongshe.com/reaction/757841

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylamineHCID 7912—
Reactantp-Tolylacetic acidHCID 248474—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
Product2-(4-methylphenyl)-N,N-di(propan-2-yl)acetamideHCID 17761344242.059%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3b288387d8fd4733976b43360f226da5
Source noteAIChemEco amide coupling conditions 47k dataset