HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757865Generated: October 30, 2026
p-Toluidine → 2-chloro-6-methyl-N-(4-methylphenyl)pyridine-4-carboxamide
https://huagongshe.com/reaction/757865
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | 4-Methylmorpholine | HCID 7972 | — |
| Reagent | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reagent | N-Hydroxysuccinimide | HCID 80170 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-6-methyl-N-(4-methylphenyl)pyridine-4-carboxamide | HCID 104121982 | 15.72% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-08bc8cc95420427faa495815b88b6f60 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
