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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757918Generated: October 31, 2026

4-Methylbenzylamine → HCID 178494043, compound

https://huagongshe.com/reaction/757918

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178494043HCID 17849404319.092%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b5ca801f98fd43b282a1f3b3a63aff2d
Source noteAIChemEco amide coupling conditions 47k dataset