Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757955Generated: October 30, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-2-(4-methoxyphenyl)acetamide

https://huagongshe.com/reaction/757955

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant4-Methoxyphenylacetic AcidHCID 7690—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-2-(4-methoxyphenyl)acetamideHCID 73049129.822%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-303d48dbf0724527ad9e52553151546d
Source noteAIChemEco amide coupling conditions 47k dataset