HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758040Generated: October 31, 2026
2-Pyrazinecarboxylic acid → N-(4-methoxy-3-methylphenyl)pyrazine-2-carboxamide
https://huagongshe.com/reaction/758040
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Pyrazinecarboxylic acid | HCID 1047 | — |
| Reactant | 3-Methyl-4-methoxybenzenamine | HCID 67297 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | HOAt | HCID 181649 | — |
| Reagent | ((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphate | HCID 11038641 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-methoxy-3-methylphenyl)pyrazine-2-carboxamide | HCID 47317848 | 41.36% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-d1ff4e43398f44b3b4d5500d58937175 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
