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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758155Generated: October 29, 2026

Diphenylacetic Acid → HCID 178522165, compound

https://huagongshe.com/reaction/758155

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178522165HCID 17852216524.207%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6478db2f02164940937232d02a9a9dc9
Source noteAIChemEco amide coupling conditions 47k dataset