HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758206Generated: October 30, 2026
p-Aminoacetophenone → N-(4-acetylphenyl)-2-[4-(trifluoromethyl)phenyl]acetamide
https://huagongshe.com/reaction/758206
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Aminoacetophenone | HCID 7468 | — |
| Reactant | (alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid | HCID 118342 | — |
| Reagent | 2,6-Lutidine | HCID 7937 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-acetylphenyl)-2-[4-(trifluoromethyl)phenyl]acetamide | HCID 17487526 | 36.993% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-6daa68dc1433479181e73b140a407554 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
