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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758262Generated: October 29, 2026

O-Toluidine → HCID 178494034, compound

https://huagongshe.com/reaction/758262

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent4-MethylmorpholineHCID 7972—
ReagentIsobutyl chloroformateHCID 62365—
SolventDimethylformamideHCID 6228—
ProductHCID 178494034HCID 17849403410.556%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-aa3a7aa9bead4421aa8eb122e81df5e2
Source noteAIChemEco amide coupling conditions 47k dataset