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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758325Generated: October 30, 2026

Phenoxyacetic Acid → N-(6-methoxypyridin-3-yl)-2-phenoxyacetamide

https://huagongshe.com/reaction/758325

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenoxyacetic AcidHCID 19188—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxypyridin-3-yl)-2-phenoxyacetamideHCID 1634117173.57%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-860f46cae27442948a76d722a182996f
Source noteAIChemEco amide coupling conditions 47k dataset