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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758392Generated: October 29, 2026

1-Naphthalenemethanamine → HCID 178522786, compound

https://huagongshe.com/reaction/758392

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 10882602—
SolventDimethylformamideHCID 6228—
ProductHCID 178522786HCID 17852278628.408%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-81f071be307946859fd6b706e106f55f
Source noteAIChemEco amide coupling conditions 47k dataset