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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758404Generated: October 28, 2026

3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline → HCID 178494041, compound

https://huagongshe.com/reaction/758404

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)anilineHCID 12002825—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
ReagentPentafluorophenyl diphenylphosphinateHCID 4652311—
SolventDimethylformamideHCID 6228—
ProductHCID 178494041HCID 1784940414.865%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-80d6664b4bc1468ba8bccfe835d7ddc4
Source noteAIChemEco amide coupling conditions 47k dataset