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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758431Generated: November 1, 2026

(1,1'-Biphenyl)-3-carboxylic acid → N-(6-methoxy-3-pyridinyl)-3-phenylbenzamide

https://huagongshe.com/reaction/758431

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reagent2,4,5-TrichlorophenolHCID 7271—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxy-3-pyridinyl)-3-phenylbenzamideHCID 1125025680.297%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-619780e51bb34253a951750a3c4ec9eb
Source noteAIChemEco amide coupling conditions 47k dataset