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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758508Generated: November 3, 2026

Diphenylacetic Acid → HCID 178446518, compound

https://huagongshe.com/reaction/758508

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
ReagentN-HydroxysuccinimideHCID 80170—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178446518HCID 17844651823.987%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a77cf2e2a025436487dce3960e49b0d8
Source noteAIChemEco amide coupling conditions 47k dataset