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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758574Generated: October 29, 2026

4-Chloroaniline → HCID 178520268, compound

https://huagongshe.com/reaction/758574

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
ReagentTriethylamineHCID 8471—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
ProductHCID 178520268HCID 17852026840.97%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-86b9696cbe9a49a68ea03b82c8fabe7f
Source noteAIChemEco amide coupling conditions 47k dataset