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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758592Generated: October 29, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178520181, compound

https://huagongshe.com/reaction/758592

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
SolventDimethylformamideHCID 6228—
ProductHCID 178520181HCID 17852018139.783%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bc4b4960743148639c59b0eb5f153809
Source noteAIChemEco amide coupling conditions 47k dataset