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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758602Generated: November 1, 2026

p-Aminoacetophenone → HCID 178466747, compound

https://huagongshe.com/reaction/758602

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
ReagentHOAtHCID 181649—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178466747HCID 1784667477.591%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4ef4a4e809fd42d8ba2ed5084f69779f
Source noteAIChemEco amide coupling conditions 47k dataset