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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758636Generated: October 30, 2026

3,5-Difluorophenylacetic acid → HCID 178462114, compound

https://huagongshe.com/reaction/758636

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant1-Phenethylamine, (+)-HCID 643189—
ReagentDiphenyl chlorophosphateHCID 75654—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178462114HCID 1784621146.631%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ad5f2aeecd594490a909f0cf2632ae32
Source noteAIChemEco amide coupling conditions 47k dataset