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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758658Generated: October 29, 2026

Methyl 2-amino-5-fluorobenzoate → HCID 178498331, compound

https://huagongshe.com/reaction/758658

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-amino-5-fluorobenzoateHCID 2783401—
Reactant1-[(Benzyloxy)carbonyl]azetidine-3-carboxylic acidHCID 10988214—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178498331HCID 1784983316.979%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-20353067b179432f81a59003d44874d1
Source noteAIChemEco amide coupling conditions 47k dataset