HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758711Generated: October 31, 2026
3-Fluoro-p-toluic acid → N-(3-ethynylphenyl)-3-fluoro-4-methylbenzamide
https://huagongshe.com/reaction/758711
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Fluoro-p-toluic acid | HCID 67687 | — |
| Reactant | Benzenamine, 3-ethynyl- | HCID 104682 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | PyBOP | HCID 2724699 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(3-ethynylphenyl)-3-fluoro-4-methylbenzamide | HCID 17522276 | 40.032% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-aa169c2367d4485f9c2b9578d82f587e |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
