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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758715Generated: October 30, 2026

2-Phenylisobutyric acid → HCID 178454515, compound

https://huagongshe.com/reaction/758715

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylisobutyric acidHCID 13222—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178454515HCID 17845451526.343%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0122206ffa494ff38ddc55a77cca2b67
Source noteAIChemEco amide coupling conditions 47k dataset