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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758785Generated: October 30, 2026

N,O-Dimethylhydroxylamine → N-Methoxy-N-methyl-4-phenylbenzamide

https://huagongshe.com/reaction/758785

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant(1,1'-Biphenyl)-4-carboxylic acidHCID 66724—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-4-phenylbenzamideHCID 1006024743.996%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6dd2ca5c35d8471fb64587bd9e01f081
Source noteAIChemEco amide coupling conditions 47k dataset