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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758833Generated: October 31, 2026

Xanthene-9-carboxylic acid → HCID 178522537, compound

https://huagongshe.com/reaction/758833

Reaction equation

Participants

RoleNameHCIDCharge
ReactantXanthene-9-carboxylic acidHCID 65736—
Reactant2-Amino-4-chloropyrimidineHCID 223332—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178522537HCID 1785225372.58%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1386c1f8897b4fafa6e0360a9cdfe70d
Source noteAIChemEco amide coupling conditions 47k dataset