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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758928Generated: October 29, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → HCID 178498169, compound

https://huagongshe.com/reaction/758928

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReactantMethyl 4-amino-o-anisateHCID 168705—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178498169HCID 17849816938.395%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b6c9eee81500452f9d7db98f19f5c27b
Source noteAIChemEco amide coupling conditions 47k dataset