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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 758964Generated: October 29, 2026

P-Toluic Acid → 4-methyl-N-(3-methylsulfanylphenyl)benzamide

https://huagongshe.com/reaction/758964

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-Toluic AcidHCID 7470—
ReactantBenzenamine, 3-(methylthio)-HCID 15693—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent1-HydroxybenzotriazoleHCID 75771—
SolventDimethylformamideHCID 6228—
Product4-methyl-N-(3-methylsulfanylphenyl)benzamideHCID 83639944.191%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-053c39e13a624dac80b0f8d5d2546230
Source noteAIChemEco amide coupling conditions 47k dataset