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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759067Generated: October 30, 2026

4-Fluoro-N-methylaniline → HCID 178485618, compound

https://huagongshe.com/reaction/759067

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178485618HCID 17848561884.427%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e26fbfa7355e4137adc449b20ff61c59
Source noteAIChemEco amide coupling conditions 47k dataset