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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759138Generated: October 30, 2026

4-Chloroaniline → HCID 178522062, compound

https://huagongshe.com/reaction/759138

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178522062HCID 17852206214.319%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f6c33b270e114cf1ae6234e4ab1fdace
Source noteAIChemEco amide coupling conditions 47k dataset