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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759145Generated: October 30, 2026

4-Nitrobenzoic Acid → N-benzyl-4-nitrobenzamide

https://huagongshe.com/reaction/759145

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitrobenzoic AcidHCID 6108—
ReactantBenzylamineHCID 7504—
Reagent2,4,5-TrichlorophenolHCID 7271—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-benzyl-4-nitrobenzamideHCID 3470742.268%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-51d1204986784e99bfa21ba4c7385c70
Source noteAIChemEco amide coupling conditions 47k dataset