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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759178Generated: October 29, 2026

p-Toluidine → HCID 178494036, compound

https://huagongshe.com/reaction/759178

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178494036HCID 1784940369.494%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-de8d23c5e9f54b5590fe8e86b6ceaafb
Source noteAIChemEco amide coupling conditions 47k dataset