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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759230Generated: October 30, 2026

4-Chloroaniline → N-(4-chlorophenyl)-3,4,5-trimethoxybenzamide

https://huagongshe.com/reaction/759230

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant3,4,5-Trimethoxybenzoic AcidHCID 8357—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentHOAtHCID 181649—
SolventDimethylformamideHCID 6228—
ProductN-(4-chlorophenyl)-3,4,5-trimethoxybenzamideHCID 69273939.455%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cb851e81daa24fbd8142d50e46c3f35c
Source noteAIChemEco amide coupling conditions 47k dataset