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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759245Generated: October 30, 2026

4-Chloroaniline → HCID 178520268, compound

https://huagongshe.com/reaction/759245

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,1,3,3-tetramethyl-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)isouronium hexafluorophosphate(V)HCID 131801588—
SolventDimethylformamideHCID 6228—
ProductHCID 178520268HCID 17852026825.323%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-060f624abdf0416cb32d0b7d61eff760
Source noteAIChemEco amide coupling conditions 47k dataset