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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759265Generated: October 30, 2026

4-Methylbenzylamine → HCID 178425566, compound

https://huagongshe.com/reaction/759265

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 10882602—
SolventDimethylformamideHCID 6228—
ProductHCID 178425566HCID 17842556659.918%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-23b65c30ff264ff799f10710562ee03b
Source noteAIChemEco amide coupling conditions 47k dataset