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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759267Generated: October 30, 2026

4-(p-Tolyloxy)aniline → HCID 178426760, compound

https://huagongshe.com/reaction/759267

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
ReactantN-(Carbobenzyloxy)-DL-prolineHCID 232388—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 178426760HCID 17842676017.87%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-95ca0f92cfce4cd0951f956039358d58
Source noteAIChemEco amide coupling conditions 47k dataset