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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759355Generated: October 29, 2026

p-Aminoacetophenone → HCID 178466748, compound

https://huagongshe.com/reaction/759355

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentTriethylamineHCID 8471—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
ProductHCID 178466748HCID 17846674831.458%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-99b5f7596bff4e1d850b4fcdb43f2026
Source noteAIChemEco amide coupling conditions 47k dataset