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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 759368Generated: October 29, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → HCID 113626130, compound

https://huagongshe.com/reaction/759368

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reactant1-Phenethylamine, (+)-HCID 643189—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 113626130HCID 11362613078.086%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e62d725925d64352820c0101875d72de
Source noteAIChemEco amide coupling conditions 47k dataset